Collagen

1.  Crowley, David C et al. “Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial.” International journal of medical sciences vol. 6,6 312-21. 9 Oct. 2009, doi:10.7150/ijms.6.312

2.  Lerman, Robert H et al. “Nutritional Approach for Relief of Joint Discomfort: A 12-week, Open-case Series and Illustrative Case Report.” Integrative medicine (Encinitas, Calif.) vol. 14,5 (2015): 52-61.

3.  Lugo, James P et al. “Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study.” Nutrition journal vol. 15 14. 29 Jan. 2016, doi:10.1186/s12937-016-0130-8

MSM

4.  L.S. Kim, L.J. Axelrod, P. Howard, N. Buratovich, R.F. Waters, Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial, Osteoarthritis and Cartilage, Volume 14, Issue 3, 2006, Pages 286-294, ISSN 1063-4584, https://doi.org/10.1016/j.joca.2005.10.003. (http://www.sciencedirect.com/science/article/pii/S1063458405002852)

Turmeric

5.  James W. Daily, Mini Yang, and Sunmin Park.Journal of Medicinal Food.Aug 2016.ahead of printhttp://doi.org/10.1089/jmf.2016.3705

6.  Funk, J.L., Frye, J.B., Oyarzo, J.N., Kuscuoglu, N., Wilson, J., McCaffrey, G., Stafford, G., Chen, G., Lantz, R.C., Jolad, S.D., Sólyom, A.M., Kiela, P.R. and Timmermann, B.N. (2006), Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis & Rheumatism, 54: 3452-3464. doi:10.1002/art.22180

Piperine

7.  https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2006-957450

8.  A. Khajuria, N. Thusu, U. Zutshi, Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics, Phytomedicine, Volume 9, Issue 3, 2002, Pages 224-231, ISSN 0944-7113, https://doi.org/10.1078/0944-7113-00114. (http://www.sciencedirect.com/science/article/pii/S0944711304701063)

 

Boswellia

9.  N. Kimmatkar, V. Thawani, L. Hingorani, R. Khiyani, Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee – A randomized double blind placebo controlled trial, Phytomedicine, Volume 10, Issue 1, 2003, Pages 3-7, ISSN 0944-7113, https://doi.org/10.1078/094471103321648593. (http://www.sciencedirect.com/science/article/pii/S0944711304701890)

10.  Sadiq Umar, Khalid Umar, Abu Hasnath Md. Golam Sarwar, Altaf Khan, Niyaz Ahmad, Sayeed Ahmad, Chandra Kant Katiyar, Syed Akhtar Husain, Haider A. Khan, Boswellia serrata extract attenuates inflammatory mediators and oxidative stress in collagen induced arthritis, Phytomedicine, Volume 21, Issue 6, 2014, Pages 847-856, ISSN 0944-7113,

https://doi.org/10.1016/j.phymed.2014.02.001. (http://www.sciencedirect.com/science/article/pii/S0944711314000750)

 

Ginger

11.  Altman, R.D. and Marcussen, K.C. (2001), Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis & Rheumatism, 44: 2531-2538. doi:10.1002/1529-0131(200111)44:11<2531::AID-ART433>3.0.CO;2-J

Bromelain

12.  Brien, Sarah et al. “Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.” Evidence-based complementary and alternative medicine : eCAM vol. 1,3 (2004): 251-257. doi:10.1093/ecam/neh035

Vitamin C

13.  Murad, S et al. “Regulation of collagen synthesis by ascorbic acid.” Proceedings of the National Academy of Sciences of the United States of America vol. 78,5 (1981): 2879-82. doi:10.1073/pnas.78.5.2879

14.  D. Darr, S. Combs, S. Pinnell, Ascorbic Acid and Collagen Synthesis: Rethinking a Role for Lipid Peroxidation, Archives of Biochemistry and Biophysics, Volume 307, Issue 2, 1993, Pages 331 335, ISSN 0003-9861, https://doi.org/10.1006/abbi.1993.1596. (http://www.sciencedirect.com/science/article/pii/S0003986183715961)

 

Magnesium

15.  https://www.researchgate.net/profile/Karim_Senni/publication/10769266_Magnesium_and_connective_tissue/links/0fcfd510110114d119000000.pdf

Zinc

16.  Effect of zinc deficiency on nucleic acids, collagen, and noncollagenous protein of the connective tissue Fernandez-Madrid, Felix et al. The Journal of Laboratory and Clinical Medicine, Volume 82, Issue 6, 951 - 961